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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4c96bde7f17e89f911aa215da9e293730ee7c1348a568377da7a18ca2a5f8fe4' 
  AND token = 'XyadloVFN7Lt4w4Oup9AyuwIln128AlyhB1R601qoDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}