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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5c8821a878c0c6ee326a021d15d30ae85edc1291d23da83cb8c2415b53d0a00f' 
  AND token = 'oHjD3dkGOMgxWQDqDc8JEdfPU65UaSLekXNcU3PTGGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}