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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a1a8bcac60e664ce906a9f337811811781d9d2a68994e109a385b99fbf27bfe4' 
  AND token = '++Ij3gxgi8HNMOo/5LQ5Ujaj8oTyaqR5TqailoEOD/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}