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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '27e8203a8faaf1c68a2810bf2e3c94f4e5ca5e023fe17f138e52b11302a54a35' 
  AND token = '+XMS9fL/KBPobb5XuekbRaqLiAoapb9vb0ORuFuULJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}