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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '078c6b5b95a9a4dae08d9d31522c74aca9ba0ba49c4047d8fdccbd12f543ff66' 
  AND token = 'fUcVb7gj3LbIn+GUwP148o5AupDSFpWZXc7L7bAED5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}