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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '708a9159012031dff014e0303aa1af626b3c8a36fe9191dbac33165e303f02c5' 
  AND token = 'bYXJgaZE93EOHiqn1BtZ6ANtLb3jH9MCoS86/nZNdY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}