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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'be281ec163062b9194f417cdc51249fd0c6ab7d2d9d1ce2a8c979567e0410d6c' 
  AND token = 'XtSAlFVAqqQiaDN0jRfHneucEOguAd+0neqOWv/piMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}