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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b54b87d0dacef94e58bb173d44669024bfc172294733681b97c10fd5005a0c81' 
  AND token = 'jF73/E3L3910x8MdjHzxTbPHxHqNtvsdO0DmeDo4ASI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}