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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b3fc2811dbc69c6bca872f00da2ee8399b7f7e2389a4aa12594f4efc8c48a892' 
  AND token = 'cRLXI5fEoGS3k/RF6nWpAa8clRXiD1jUC8nuQCnmofI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}