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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ce91ebf6106b562a1a409ad6f24107c5dd28aaa59653ac60c572154701d12b20' 
  AND token = 'aOZ9KQlmJ6XpbGeZB1fccm3eU/JTMx06cjW7cLkUkh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}