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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f8a4b6f7eb8f8f9cd2985aefadc4c7948e191c356e38bf11c8acf7d7b44c172b' 
  AND token = 'x+q07vb/wAu1pmD/XKCn0X9v6VCeqYYbOiFp93F7C8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}