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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bc87620e89aa45d905208531355d7136d6d901bec0489f483f907af95ce3a114' 
  AND token = 'InbaNNQem4htHOkhQcoPVGena4zUfl1yKAvXSc1C6oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}