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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'eceabec5e2cbc8ed960ffb7e8ade42463b2b06c0bb24708286939c04395fd505' 
  AND token = 'aWoO8Cu9jm2axQKBGZAtL+ImHFSNxWwyBy3/PAaMSTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}