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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '79a5deecc366de8a57710c3e381d291fb0abfda1307b6e7c8148d4dec15c2ccc' 
  AND token = 'DT2MfRPaqCMnWRLEGuVuLlodigC3WkW9bJLewhY1peo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}