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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4d2275288e567109baae697dd6a3e647a85ee328fb8b4f230ba52bdcdbe8d531' 
  AND token = '5PY+j4pBHVvjVk9Nh9tjWb+chm70FnYnYNRca8QH2lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}