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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f22c6e8257ec4653c0aa40bb38a7756741556d204de00e6f95e656493c72345d' 
  AND token = 'WG1azcS8aNqkMqE1XqAHfYh0qiCX7IIKbeSKxeifCpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}