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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8332f6d30b14ed96c045c3736b6051a91f6b5fe30cf7b542be3d71d934712cab' 
  AND token = 'Ek0aZtUnX9Ug2FEzY7x7DZhih+tIUW9U4entpmNksic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}