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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '51132c3f9fac3ce29186712c846ba57ceb34ed63ae33c380f98d71c172e73a1f' 
  AND token = 'NGhWaog8R5yrnuOEWC9noYDCOWpO/1V4/HZ8yAmhbg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}