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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '078fcc3ddd57e00723952b835e5ab2a24fce7cdc8ec270810884a43aa40d8498' 
  AND token = 'S++SwTO40TyM3V0uOmtmlnIdJDdNeByqWs2YwuahQR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}