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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ed35cb0388028e621fbcd217eee977ba879c0a151bcf04b9534294fc818aad9c' 
  AND token = 'ancQHhop9fxoK2DSR7WCKYt1npTtIt6MexwfhWAqKzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}