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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6a1c326c652e378adbe320f273a6fb165c4be37619d6a8d7364f5890ce2c4464' 
  AND token = 'HvKmbcp8N8C5mywmXxdjlhy875OOG6MUo6yRvxiDIYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}