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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '46f81d97e904354fb24eeccac4d814cf480e5ddc5906f8e0b0c084e035d57ccb' 
  AND token = 'p907Zy40irs6C6ds+ifoTwcXzhAyJNlw8yp1FZP8zsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}