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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c1645feec60a15e64c4e96ee8833d3ba020f7a78aed8ad852e7d87d912fb77e3' 
  AND token = 'Hy0DPkH0Iws6BbMa4/sPRUnliOnAAd7Vr36UEMVFdAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}