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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd043f98e133159b00e86eb39b5429d6d28ab14d8561d43b2f120f459e390ddf4' 
  AND token = '44DWyy3OMk1QPfvSMcREvbTdK1woE7caASvrnAPWHdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}