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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '25ade3e88914c439173c8fe3996732f68ee5649a78e0041ab03fefa11d0cf1d3' 
  AND token = 'sbHeAkJEoD+qusO2ncHzI37ZQEw4eNBc3B0NBU0bGW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}