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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4fe80c020a1270a7b05fa4c83aa9342ac1ba743ba8ccc52cbab15e507b2f1856' 
  AND token = 'aFz9b90ivqX45sSmONEtQhl8P9li3clLqTsiZx3XMVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}