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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2b3506d8121a0760bb4b058e139e1c6092b801ea48c177a3d205c605d97d198b' 
  AND token = '6zz0t6gXx1f8kmcSCpFOjIU3TPZAD3KArLTZwRiQU2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}