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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0452649c67ebb36ccc1095c11bef1461f7737f75abec99aed5258f51d12119e9' 
  AND token = 'Kex9CzLiuUgBx4qJCmaJoW59quAMgxQs7Ug768g0720=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}