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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'fb850b01191ddebe74f382c6f353763a293b9b21b3884a5deabc08522d1ccc88' 
  AND token = 'yXwhXTqeQVTtAsskDiOsoHIWavWnons3EaetA4fy6I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}