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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c474472c94afecd067f737a6f62e708dd29eadd642d012442b3e5bb8df7c75a9' 
  AND token = 'nfiEw1asifFlWt05ze+Z1ieXaMRO6A8h767uAxCm9T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}