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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '487efb6b142d5219a583d16ed4342c448b4396baca1cf88e967efd1b35ec7888' 
  AND token = 'xQzLzHSyOyW/6XsyCm+/j2xqbDKVj/aldWGkMKlytPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}