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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e42d2473b84e095faa568c03b2aabfcbfa539bd4571e7c910608265b04598577' 
  AND token = '5gaDkG5GNgIknK1kOeSEHTslJOAjxk2by+U2+ONVdxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}