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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0cb367e96937f7412778b04d9fa3bed93db42a232cce2216d8ceaaf0da6d7806' 
  AND token = 'O+0Z4n3ABE6wZ6a8Htxs+GNKWOIOmnok23KnCI8+ekI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}