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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'cecc3c20c2b475c9786a240f91fe0b3afe35c25b1ed021259a8a0ecc5021b533' 
  AND token = 'ithTKCR8O0c9hJpJfhepJQSoxrPR+i2/exiQZ0jEP8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}