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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8b49dad8a81f0c44e16972450076812b01397434f1382b4f742b8b7c495831d7' 
  AND token = '8rjoYoewmItSGfQkMxarjY7Y4OwoSjzm8gelhpExBdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}