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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4224de3d348f1cca51e2ac3c1ef26b5ae7c472dd7de0f5f0a6e41e7a970a6f67' 
  AND token = 'AphtwsM6b8Pw1lZmKuDrDFdmzBOw5vN0qnVmr7IdVSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}