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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f4d2705709dd74da16ca6354b958321c50a45a9aed11b05bb79680f260230a5e' 
  AND token = '8x0Cy4p198sruxerUsDst5xT3X/AaomImH4fDbJ9Vsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}