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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '457f37afdad6045f61a434479de43bced0588a0cc7e510143fb5be1b0c358875' 
  AND token = 'JmAM8L5HiPAu1mHFJCQNz0uT7fW6o88U7LRrq76oi1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}