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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '981baff3bda2e929c7a2b07491ece409ecb9e60d968c4a335c5345892f61a11d' 
  AND token = 'j4vEtHsVfCOtPk6bkcSqtCo82biAPfzpYqGJT29HFWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}