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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '421f5bc034e6c831531baaa7d5e765e8183f1c92e68feb02eee571e40dd4b4ec' 
  AND token = '7yXN+qF0eKC5mc+dFUe5y12WvWohChQqQwgovtYx+ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}