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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e22cbacd78280817065229ab18352490c9328115acc8e6847c7aeb95e5128958' 
  AND token = 'wIUAWMnxf9xsQ9D+bv/LTJnUVdETsfjwoc8bM/mDbt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}