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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '45a72698ef650a67ad708d7d544d1e2c7289b0e6b433a49af837f50d100f1a3c' 
  AND token = 'nE7rQsdynyk7g5FzwYEUWyv7Ok11OGkTqJdOACLgd7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}