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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'da4d5a011ab49b607f9233e17f8ec6e8135cbf01f40590948021214be0b6536b' 
  AND token = 'BuoO5h0kW8OgJjtXJsupyYSKisIichR6p5kYm00/BME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}