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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7abfc05c60084355b389e1024c96c1938f173aef94082f4e6e243caa276af379' 
  AND token = 't60HDvLBShommFh3R8EkeqosMblu1E8gufhDAiXg5Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}