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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd54bdf6ceb0aabdec02402b51893eb2203c5405d4237d078d210476b2c5891ab' 
  AND token = 'cYDPsylZDc4DlL/e31diGyJTOLLidI4tgNcDPdiF0Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}