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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '44c2459f067a12ad4b9a1400a7cccbfc8ce5045910ee4517a672df4879186e18' 
  AND token = 'NgIInZPJ209t9hDr6mMqnsy92u2GyNDtZ0SBE/Le9OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}