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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c160cb9a5e14f9213bfbb8968f64d5a31755c9e197ebe64a8bcab86262023286' 
  AND token = 'in7Q9tyecu+MyeGj7WbYBEpmA8h+HrKqSLsU1P74dBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}