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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '68481190797456866d7c69fac2e6f4ee49c0ad4a4096982ed75dba555ac91d21' 
  AND token = 'EYbxOQ31TLZte98/kkpUSVK7poMnqb28qxO0dXgZAE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}