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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8275c328f22673d8b00498ed28b8e0c018fcc2596fda5b881c44cf894d49e028' 
  AND token = 'Z5VJvT02BEsXGQFHN9cJ/dUrMGkIBa7F7MZuz17ptfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}