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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '44dd478a745d4070bf9c732ef1a568a82e88e31e90fbeb5cfd61aabfdf266421' 
  AND token = 'mxRdXj+2FWi0CPcQ7l2i8lZXgaVLDokCyaApLxtA+dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}